All models are wrong and yours are useless - making clinical prediction models impactful for patients

Sep 1, 2025·
Prof. Dr. Florian Markowetz

Abstract:

Most published clinical prediction models are never used in clinical practice and there is a huge gap between academic research and clinical implementation. Here, I propose ways for academic researchers to be proactive partners in improving clinical practice and to design models in ways that ultimately benefit patients.

About Florian:

Florian Markowetz is Professor of Computational Oncology at the University of Cambridge and Senior Group Leader at the Cancer Research UK Cambridge Institute. He is a Royal Society Wolfson Research Merit Award holder and received a CRUK Future Leader in Cancer Research prize. He holds degrees in Mathematics (Dipl. math.) and Philosophy (M.A.) from the University of Heidelberg and a Dr. rer. nat. in Computational Biology from Free University Berlin, for which he was awarded an Otto-Hahn Medal by the Max Planck Society. He is a co-founder and director of Tailor Bio, a pancancer precision medicine start-up.